You will most likely need to rearrange or fine-tune settings for monitors after connecting to a docking station.
To change monitor settings you need to right click anywhere empty on your desktop and select "Display Settings".
Problem: Mouse won't go across monitors (or goes from wrong side)
Solution: You should see a diagram of some monitors. Click the "Identify" button to show which monitor is identified with which number. You will likely need to move the monitors in the diagram to accurately represent how they are actually physically arranged. I.E. the diagram will show monitor 1 and then monitor 2 to the right of it, but maybe your monitors are arranged 2 and then 1, so click and drag Monitor 2 to the left of Monitor 1.
Problem: Monitors all show the same thing
Solution: Scroll down to the bottom and under the "Multiple Displays" drop down select "Extend these displays".
Problem: Icons on wrong monitor
Solution: Select which monitor you want them to be on at the top and then scroll down to the "Multiple Displays" section and check the box for "Make this my main display"
Additionally, you can read the how-to links below from Microsoft for instructions on adjusting your external monitors:
Set up dual monitors on Windows 10